Fosfomycin disodium salt
Brand names,
Fosfomycin disodium salt
Analogs
Fosfomycin disodium salt
Brand Names Mixture
- Micardis Plus (Hydrochlorothiazide + Telmisartan)
Fosfomycin disodium salt
Chemical_Formula
C3H7O4P
Fosfomycin disodium salt
RX_link
http://www.rxlist.com/cgi/generic2/fosfomycin.htm
Fosfomycin disodium salt
fda sheet
Fosfomycin disodium salt
msds (material safety sheet)
Fosfomycin disodium salt
Synthesis Reference
No information avaliable
Fosfomycin disodium salt
Molecular Weight
138.059 g/mol
Fosfomycin disodium salt
Melting Point
94 oC
Fosfomycin disodium salt
H2O Solubility
50 mg/mL (Sodium salt)
Fosfomycin disodium salt
State
Solid
Fosfomycin disodium salt
LogP
-0.912
Fosfomycin disodium salt
Dosage Forms
Powder
Fosfomycin disodium salt
Indication
For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.
Fosfomycin disodium salt
Pharmacology
Fosfomycin is a broad spectrum antibiotic that concentrates in kidney and bladder and is used to treat uncomplicated urinary tract infections. Fosfomycin also reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.
Fosfomycin disodium salt
Absorption
Fosfomycin tromethamine is rapidly absorbed following oral administration and converted to fosfomycin. Oral bioavailability under fasting conditions is 37%. When given with food, oral bioavailability is reduced to 30%
Fosfomycin disodium salt
side effects and Toxicity
LD50>5 g/kg (rats). Side effects may include diarrhea
Fosfomycin disodium salt
Patient Information
No information avaliable
Fosfomycin disodium salt
Organisms Affected
E. coli and other enteric bacteria