Veramina
Brand names,
Veramina
Analogs
Veramina
Brand Names Mixture
- Micardis Plus (Hydrochlorothiazide + Telmisartan)
Veramina
Chemical_Formula
C3H7O4P
Veramina
RX_link
http://www.rxlist.com/cgi/generic2/fosfomycin.htm
Veramina
fda sheet
Veramina
msds (material safety sheet)
Veramina
Synthesis Reference
No information avaliable
Veramina
Molecular Weight
138.059 g/mol
Veramina
Melting Point
94 oC
Veramina
H2O Solubility
50 mg/mL (Sodium salt)
Veramina
State
Solid
Veramina
LogP
-0.912
Veramina
Dosage Forms
Powder
Veramina
Indication
For the treatment of uncomplicated urinary tract infections (acute cystitis) in women due to susceptible strains of Escherichia coli and Enterococcus faecalis.
Veramina
Pharmacology
Fosfomycin is a broad spectrum antibiotic that concentrates in kidney and bladder and is used to treat uncomplicated urinary tract infections. Fosfomycin also reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents.
Veramina
Absorption
Fosfomycin tromethamine is rapidly absorbed following oral administration and converted to fosfomycin. Oral bioavailability under fasting conditions is 37%. When given with food, oral bioavailability is reduced to 30%
Veramina
side effects and Toxicity
LD50>5 g/kg (rats). Side effects may include diarrhea
Veramina
Patient Information
No information avaliable
Veramina
Organisms Affected
E. coli and other enteric bacteria