Etanercept
Brand names,
Etanercept
Analogs
Etanercept
Brand Names Mixture
Etanercept
Chemical_Formula
C2224H3475N621O698S36
Etanercept
RX_link
http://www.rxlist.com/cgi/generic/etanercept.htm
Etanercept
fda sheet
Etanercept
msds (material safety sheet)
Etanercept
Synthesis Reference
No information avaliable
Etanercept
Molecular Weight
51234.9
Etanercept
Melting Point
71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Etanercept
H2O Solubility
No information avaliable
Etanercept
State
Liquid
Etanercept
LogP
-0.529
Etanercept
Dosage Forms
Kit;liquid;powder for solution
Etanercept
Indication
For treatment of severe adult and juvenille rheumatoid arthritis
Etanercept
Pharmacology
Used in the treatment of rheumatoid arthritis and the reduction of the adverse effects of tumor necrosis factor (TNF). TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in tissues and fluids of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Etanercept binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.
Etanercept
Absorption
No information avaliable
Etanercept
side effects and Toxicity
No information avaliable
Etanercept
Patient Information
BIOD00052.html
Etanercept
Organisms Affected
Humans and other mammals