CD120b
Brand names,
CD120b
Analogs
CD120b
Brand Names Mixture
CD120b
Chemical_Formula
C2224H3475N621O698S36
CD120b
RX_link
http://www.rxlist.com/cgi/generic/etanercept.htm
CD120b
fda sheet
CD120b
msds (material safety sheet)
CD120b
Synthesis Reference
No information avaliable
CD120b
Molecular Weight
51234.9
CD120b
Melting Point
71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
CD120b
H2O Solubility
No information avaliable
CD120b
State
Liquid
CD120b
LogP
-0.529
CD120b
Dosage Forms
Kit;liquid;powder for solution
CD120b
Indication
For treatment of severe adult and juvenille rheumatoid arthritis
CD120b
Pharmacology
Used in the treatment of rheumatoid arthritis and the reduction of the adverse effects of tumor necrosis factor (TNF). TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in tissues and fluids of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Etanercept binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.
CD120b
Absorption
No information avaliable
CD120b
side effects and Toxicity
No information avaliable
CD120b
Patient Information
BIOD00052.html
CD120b
Organisms Affected
Humans and other mammals