Enbrel (Immunex Corp)
Brand names,
Enbrel (Immunex Corp)
Analogs
Enbrel (Immunex Corp)
Brand Names Mixture
Enbrel (Immunex Corp)
Chemical_Formula
C2224H3475N621O698S36
Enbrel (Immunex Corp)
RX_link
http://www.rxlist.com/cgi/generic/etanercept.htm
Enbrel (Immunex Corp)
fda sheet
Enbrel (Immunex Corp)
msds (material safety sheet)
Enbrel (Immunex Corp)
Synthesis Reference
No information avaliable
Enbrel (Immunex Corp)
Molecular Weight
51234.9
Enbrel (Immunex Corp)
Melting Point
71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Enbrel (Immunex Corp)
H2O Solubility
No information avaliable
Enbrel (Immunex Corp)
State
Liquid
Enbrel (Immunex Corp)
LogP
-0.529
Enbrel (Immunex Corp)
Dosage Forms
Kit;liquid;powder for solution
Enbrel (Immunex Corp)
Indication
For treatment of severe adult and juvenille rheumatoid arthritis
Enbrel (Immunex Corp)
Pharmacology
Used in the treatment of rheumatoid arthritis and the reduction of the adverse effects of tumor necrosis factor (TNF). TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in tissues and fluids of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Etanercept binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.
Enbrel (Immunex Corp)
Absorption
No information avaliable
Enbrel (Immunex Corp)
side effects and Toxicity
No information avaliable
Enbrel (Immunex Corp)
Patient Information
BIOD00052.html
Enbrel (Immunex Corp)
Organisms Affected
Humans and other mammals