p80 TNF-alpha receptor
Brand names,
p80 TNF-alpha receptor
Analogs
p80 TNF-alpha receptor
Brand Names Mixture
p80 TNF-alpha receptor
Chemical_Formula
C2224H3475N621O698S36
p80 TNF-alpha receptor
RX_link
http://www.rxlist.com/cgi/generic/etanercept.htm
p80 TNF-alpha receptor
fda sheet
p80 TNF-alpha receptor
msds (material safety sheet)
p80 TNF-alpha receptor
Synthesis Reference
No information avaliable
p80 TNF-alpha receptor
Molecular Weight
51234.9
p80 TNF-alpha receptor
Melting Point
71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
p80 TNF-alpha receptor
H2O Solubility
No information avaliable
p80 TNF-alpha receptor
State
Liquid
p80 TNF-alpha receptor
LogP
-0.529
p80 TNF-alpha receptor
Dosage Forms
Kit;liquid;powder for solution
p80 TNF-alpha receptor
Indication
For treatment of severe adult and juvenille rheumatoid arthritis
p80 TNF-alpha receptor
Pharmacology
Used in the treatment of rheumatoid arthritis and the reduction of the adverse effects of tumor necrosis factor (TNF). TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in tissues and fluids of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Etanercept binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.
p80 TNF-alpha receptor
Absorption
No information avaliable
p80 TNF-alpha receptor
side effects and Toxicity
No information avaliable
p80 TNF-alpha receptor
Patient Information
BIOD00052.html
p80 TNF-alpha receptor
Organisms Affected
Humans and other mammals