TNF-R2
Brand names,
TNF-R2
Analogs
TNF-R2
Brand Names Mixture
TNF-R2
Chemical_Formula
C2224H3475N621O698S36
TNF-R2
RX_link
http://www.rxlist.com/cgi/generic/etanercept.htm
TNF-R2
fda sheet
TNF-R2
msds (material safety sheet)
TNF-R2
Synthesis Reference
No information avaliable
TNF-R2
Molecular Weight
51234.9
TNF-R2
Melting Point
71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
TNF-R2
H2O Solubility
No information avaliable
TNF-R2
State
Liquid
TNF-R2
LogP
-0.529
TNF-R2
Dosage Forms
Kit;liquid;powder for solution
TNF-R2
Indication
For treatment of severe adult and juvenille rheumatoid arthritis
TNF-R2
Pharmacology
Used in the treatment of rheumatoid arthritis and the reduction of the adverse effects of tumor necrosis factor (TNF). TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in tissues and fluids of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Etanercept binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.
TNF-R2
Absorption
No information avaliable
TNF-R2
side effects and Toxicity
No information avaliable
TNF-R2
Patient Information
BIOD00052.html
TNF-R2
Organisms Affected
Humans and other mammals