Tumor necrosis factor receptor type II
Brand names,
Tumor necrosis factor receptor type II
Analogs
Tumor necrosis factor receptor type II
Brand Names Mixture
Tumor necrosis factor receptor type II
Chemical_Formula
C2224H3475N621O698S36
Tumor necrosis factor receptor type II
RX_link
http://www.rxlist.com/cgi/generic/etanercept.htm
Tumor necrosis factor receptor type II
fda sheet
Tumor necrosis factor receptor type II
msds (material safety sheet)
Tumor necrosis factor receptor type II
Synthesis Reference
No information avaliable
Tumor necrosis factor receptor type II
Molecular Weight
51234.9
Tumor necrosis factor receptor type II
Melting Point
71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
Tumor necrosis factor receptor type II
H2O Solubility
No information avaliable
Tumor necrosis factor receptor type II
State
Liquid
Tumor necrosis factor receptor type II
LogP
-0.529
Tumor necrosis factor receptor type II
Dosage Forms
Kit;liquid;powder for solution
Tumor necrosis factor receptor type II
Indication
For treatment of severe adult and juvenille rheumatoid arthritis
Tumor necrosis factor receptor type II
Pharmacology
Used in the treatment of rheumatoid arthritis and the reduction of the adverse effects of tumor necrosis factor (TNF). TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in tissues and fluids of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Etanercept binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.
Tumor necrosis factor receptor type II
Absorption
No information avaliable
Tumor necrosis factor receptor type II
side effects and Toxicity
No information avaliable
Tumor necrosis factor receptor type II
Patient Information
BIOD00052.html
Tumor necrosis factor receptor type II
Organisms Affected
Humans and other mammals