p75
p75 Brand names, p75 Analogs
p75 Brand Names Mixture
- No information avaliable
p75 Chemical_Formula
C2224H3475N621O698S36
p75 RX_link
http://www.rxlist.com/cgi/generic/etanercept.htm
p75 fda sheet
p75 msds (material safety sheet)
p75 Synthesis Reference
No information avaliable
p75 Molecular Weight
51234.9
p75 Melting Point
71 oC (whole mAb) - Vermeer, A.W.P. & Norde, W., Biophys. J. 78:394-404 (2000).
p75 H2O Solubility
No information avaliable
p75 State
Liquid
p75 LogP
-0.529
p75 Dosage Forms
Kit;liquid;powder for solution
p75 Indication
For treatment of severe adult and juvenille rheumatoid arthritis
p75 Pharmacology
Used in the treatment of rheumatoid arthritis and the reduction of the adverse effects of tumor necrosis factor (TNF). TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in tissues and fluids of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Etanercept binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors.
p75 Absorption
No information avaliable
p75 side effects and Toxicity
No information avaliable
p75 Patient Information
BIOD00052.html
p75 Organisms Affected
Humans and other mammals
