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Elipten Brand names, Elipten Analogs

Elipten Brand Names Mixture

  • No information avaliable

Elipten Chemical_Formula


Elipten RX_link


Elipten fda sheet

Elipten FDA

Elipten msds (material safety sheet)

Elipten Synthesis Reference

Hoffmann, Urech, U.S. pat. 2,848,455 (1958 to Ciba)

Elipten Molecular Weight

232.278 g/mol

Elipten Melting Point

149-150 oC

Elipten H2O Solubility

Practically insoluble in water

Elipten State


Elipten LogP


Elipten Dosage Forms

Tablet (250 mg)

Elipten Indication

For the suppression of adrenal function in selected patients with Cushing's syndrome, malignant neoplasm of the female breast, and carcinoma in situ of the breast.

Elipten Pharmacology

Aminoglutethimide inhibits the enzymatic conversion of cholesterol to D5-pregnenolone, resulting in a decrease in the production of adrenal glucocorticoids, mineralocorticoids, estrogens, and androgens.

Elipten Absorption

Rapidly and completely absorbed from gastrointestinal tract. The bioavailability of tablets is equivalent to equal doses given as a solution.

Elipten side effects and Toxicity

Oral LD50s (mg/kg): rats, 1800; dogs, >100. Intravenous LD50s (mg/kg): rats, 156; dogs, >100. Symptoms of overdose include respiratory depression, hypoventilation, hypotension, hypovolemic shock due to dehydration, somnolence, lethargy, coma, ataxia, dizziness, fatigue, nausea, and vomiting.

Elipten Patient Information

Elipten Organisms Affected

Humans and other mammals