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Cytadren Brand names, Cytadren Analogs

Cytadren Brand Names Mixture

  • No information avaliable

Cytadren Chemical_Formula


Cytadren RX_link

Cytadren fda sheet

Cytadren FDA

Cytadren msds (material safety sheet)

Cytadren Synthesis Reference

Hoffmann, Urech, U.S. pat. 2,848,455 (1958 to Ciba)

Cytadren Molecular Weight

232.278 g/mol

Cytadren Melting Point

149-150 oC

Cytadren H2O Solubility

Practically insoluble in water

Cytadren State


Cytadren LogP


Cytadren Dosage Forms

Tablet (250 mg)

Cytadren Indication

For the suppression of adrenal function in selected patients with Cushing's syndrome, malignant neoplasm of the female breast, and carcinoma in situ of the breast.

Cytadren Pharmacology

Aminoglutethimide inhibits the enzymatic conversion of cholesterol to D5-pregnenolone, resulting in a decrease in the production of adrenal glucocorticoids, mineralocorticoids, estrogens, and androgens.

Cytadren Absorption

Rapidly and completely absorbed from gastrointestinal tract. The bioavailability of tablets is equivalent to equal doses given as a solution.

Cytadren side effects and Toxicity

Oral LD50s (mg/kg): rats, 1800; dogs, >100. Intravenous LD50s (mg/kg): rats, 156; dogs, >100. Symptoms of overdose include respiratory depression, hypoventilation, hypotension, hypovolemic shock due to dehydration, somnolence, lethargy, coma, ataxia, dizziness, fatigue, nausea, and vomiting.

Cytadren Patient Information

Cytadren Organisms Affected

Humans and other mammals