Eletriptan
Eletriptan Brand names, Eletriptan Analogs
Eletriptan Brand Names Mixture
- No information avaliable
Eletriptan Chemical_Formula
C22H26N2O2S
Eletriptan RX_link
http://www.rxlist.com/cgi/generic3/relpax.htm
Eletriptan fda sheet
Eletriptan msds (material safety sheet)
Eletriptan Synthesis Reference
No information avaliable
Eletriptan Molecular Weight
382.52 g/mol
Eletriptan Melting Point
No information avaliable
Eletriptan H2O Solubility
Readily soluble as hydrobromide formulation
Eletriptan State
Solid
Eletriptan LogP
3.587
Eletriptan Dosage Forms
Tablet for oral administration (24.2 or 48.5 mg)
Eletriptan Indication
For the acute treatment of migraine with or without aura in adults.
Eletriptan Pharmacology
Eletriptan is a selective 5-hydroxytryptamine 1B/1D receptor agonist. In the anesthetized dog, eletriptan has been shown to reduce carotid arterial blood flow, with only a small increase in arterial blood pressure at high doses. While the effect on blood flow was selective for the carotid arterial bed, decreases in coronary artery diameter were observed. Eletriptan has also been shown to inhibit trigeminal nerve activity in the rat.
Eletriptan Absorption
Well absorbed after oral administration with a mean absolute bioavailability of approximately 50%.
Eletriptan side effects and Toxicity
Based on the pharmacology of the 5-HT1B/1D agonists, hypertension or other more serious cardiovascular symptoms could occur on overdose.
Eletriptan Patient Information
No information avaliable
Eletriptan Organisms Affected
Humans and other mammals
