Diclonina
Brand names,
Diclonina
Analogs
Diclonina
Brand Names Mixture
Diclonina
Chemical_Formula
C22H26N2O2S
Diclonina
RX_link
http://www.rxlist.com/cgi/generic3/relpax.htm
Diclonina
fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
Diclonina
Molecular Weight
382.52 g/mol
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Melting Point
No information avaliable
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H2O Solubility
Readily soluble as hydrobromide formulation
Diclonina
State
Solid
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LogP
3.587
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Dosage Forms
Tablet for oral administration (24.2 or 48.5 mg)
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Indication
For the acute treatment of migraine with or without aura in adults.
Diclonina
Pharmacology
Eletriptan is a selective 5-hydroxytryptamine 1B/1D receptor agonist. In the anesthetized dog, eletriptan has been shown to reduce carotid arterial blood flow, with only a small increase in arterial blood pressure at high doses. While the effect on blood flow was selective for the carotid arterial bed, decreases in coronary artery diameter were observed. Eletriptan has also been shown to inhibit trigeminal nerve activity in the rat.
Diclonina
Absorption
Well absorbed after oral administration with a mean absolute bioavailability of approximately 50%.
Diclonina
side effects and Toxicity
Based on the pharmacology of the 5-HT1B/1D agonists, hypertension or other more serious cardiovascular symptoms could occur on overdose.
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Patient Information
No information avaliable
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Organisms Affected
Humans and other mammals