Tanaclone
Tanaclone Brand names, Tanaclone Analogs
Tanaclone Brand Names Mixture
- No information avaliable
Tanaclone Chemical_Formula
C22H26N2O2S
Tanaclone RX_link
http://www.rxlist.com/cgi/generic3/relpax.htm
Tanaclone fda sheet
Tanaclone msds (material safety sheet)
Tanaclone Synthesis Reference
No information avaliable
Tanaclone Molecular Weight
382.52 g/mol
Tanaclone Melting Point
No information avaliable
Tanaclone H2O Solubility
Readily soluble as hydrobromide formulation
Tanaclone State
Solid
Tanaclone LogP
3.587
Tanaclone Dosage Forms
Tablet for oral administration (24.2 or 48.5 mg)
Tanaclone Indication
For the acute treatment of migraine with or without aura in adults.
Tanaclone Pharmacology
Eletriptan is a selective 5-hydroxytryptamine 1B/1D receptor agonist. In the anesthetized dog, eletriptan has been shown to reduce carotid arterial blood flow, with only a small increase in arterial blood pressure at high doses. While the effect on blood flow was selective for the carotid arterial bed, decreases in coronary artery diameter were observed. Eletriptan has also been shown to inhibit trigeminal nerve activity in the rat.
Tanaclone Absorption
Well absorbed after oral administration with a mean absolute bioavailability of approximately 50%.
Tanaclone side effects and Toxicity
Based on the pharmacology of the 5-HT1B/1D agonists, hypertension or other more serious cardiovascular symptoms could occur on overdose.
Tanaclone Patient Information
No information avaliable
Tanaclone Organisms Affected
Humans and other mammals
