Diclonia
Brand names,
Diclonia
Analogs
Diclonia
Brand Names Mixture
Diclonia
Chemical_Formula
C22H26N2O2S
Diclonia
RX_link
http://www.rxlist.com/cgi/generic3/relpax.htm
Diclonia
fda sheet
Diclonia
msds (material safety sheet)
Diclonia
Synthesis Reference
No information avaliable
Diclonia
Molecular Weight
382.52 g/mol
Diclonia
Melting Point
No information avaliable
Diclonia
H2O Solubility
Readily soluble as hydrobromide formulation
Diclonia
State
Solid
Diclonia
LogP
3.587
Diclonia
Dosage Forms
Tablet for oral administration (24.2 or 48.5 mg)
Diclonia
Indication
For the acute treatment of migraine with or without aura in adults.
Diclonia
Pharmacology
Eletriptan is a selective 5-hydroxytryptamine 1B/1D receptor agonist. In the anesthetized dog, eletriptan has been shown to reduce carotid arterial blood flow, with only a small increase in arterial blood pressure at high doses. While the effect on blood flow was selective for the carotid arterial bed, decreases in coronary artery diameter were observed. Eletriptan has also been shown to inhibit trigeminal nerve activity in the rat.
Diclonia
Absorption
Well absorbed after oral administration with a mean absolute bioavailability of approximately 50%.
Diclonia
side effects and Toxicity
Based on the pharmacology of the 5-HT1B/1D agonists, hypertension or other more serious cardiovascular symptoms could occur on overdose.
Diclonia
Patient Information
No information avaliable
Diclonia
Organisms Affected
Humans and other mammals