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Dolsinal Brand names, Dolsinal Analogs

Dolsinal Brand Names Mixture

  • No information avaliable

Dolsinal Chemical_Formula


Dolsinal RX_link

Dolsinal fda sheet

Dolsinal FDA

Dolsinal msds (material safety sheet)

Dolsinal MSDS

Dolsinal Synthesis Reference

No information avaliable

Dolsinal Molecular Weight

232.235 g/mol

Dolsinal Melting Point

229.5 oC

Dolsinal H2O Solubility

100 mg/L

Dolsinal State


Dolsinal LogP


Dolsinal Dosage Forms

Suspension (250 mg/5 mL tsp); Tablets (1000 mg, 500 mg, 250 mg)

Dolsinal Indication

For the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of E. Coli, Enterobacter species, Klebsiella species, and Proteus species.

Dolsinal Pharmacology

Nalidixic acid is a quinolone antibacterial agent for oral administration. Nalidixic acid has marked antibacterial activity against gram-negative bacteria including Enterobacter species, Escherichia coli, Morganella Morganii; Proteus Mirabilis, Proteus vulgaris, and Providencia rettgeri. Pseudomonas species are generally resistant to the drug. Nalidixic acid is bactericidal and is effective over the entire urinary pH range. Conventional chromosomal resistance to nalidixic acid taken in full dosage has been reported to emerge in approximately 2 to 14 percent of patients during treatment; however, bacterial resistance to nalidixic acid has not been shown to be transferable via R factor.

Dolsinal Absorption

Following oral administration, nalidixic acid is rapidly absorbed from the gastrointestinal tract. Bioavailability is approximately 96%. Absorption may be delayed if taken with antacids.

Dolsinal side effects and Toxicity

ORAL (LD50): Acute: 1160 mg/kg [Rat]. 572 mg/kg [Mouse]. Toxic psychosis, convulsions, increased intracranial pressure, or metabolic acidosis may occur in patients taking more than the recommended dosage. Vomiting, nausea, and lethargy may also occur following overdosage.

Dolsinal Patient Information

Dolsinal Organisms Affected

Enteric bacteria and other eubacteria