Balmox

Balmox Brand names, Balmox Analogs

Balmox Brand Names Mixture

No information avaliable

Balmox Chemical_Formula

C₁₂H₁₂N₂O₃

Balmox RX_link

http://www.rxlist.com/cgi/generic2/nalidixicacid.htm

Balmox fda sheet

Balmox FDA

Balmox msds (material safety sheet)

Balmox MSDS

Balmox Synthesis Reference

No information avaliable

Balmox Molecular Weight

232.235 g/mol

Balmox Melting Point

229.5 ^oC

Balmox H₂O Solubility

100 mg/L

Balmox State

Solid

Balmox LogP

0.949

Balmox Dosage Forms

Suspension (250 mg/5 mL tsp); Tablets (1000 mg, 500 mg, 250 mg)

Balmox Indication

For the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of E. Coli, Enterobacter species, Klebsiella species, and Proteus species.

Balmox Pharmacology

Nalidixic acid is a quinolone antibacterial agent for oral administration. Nalidixic acid has marked antibacterial activity against gram-negative bacteria including Enterobacter species, Escherichia coli, Morganella Morganii; Proteus Mirabilis, Proteus vulgaris, and Providencia rettgeri. Pseudomonas species are generally resistant to the drug. Nalidixic acid is bactericidal and is effective over the entire urinary pH range. Conventional chromosomal resistance to nalidixic acid taken in full dosage has been reported to emerge in approximately 2 to 14 percent of patients during treatment; however, bacterial resistance to nalidixic acid has not been shown to be transferable via R factor.

Balmox Absorption

Following oral administration, nalidixic acid is rapidly absorbed from the gastrointestinal tract. Bioavailability is approximately 96%. Absorption may be delayed if taken with antacids.

Balmox side effects and Toxicity

ORAL (LD₅₀): Acute: 1160 mg/kg [Rat]. 572 mg/kg [Mouse]. Toxic psychosis, convulsions, increased intracranial pressure, or metabolic acidosis may occur in patients taking more than the recommended dosage. Vomiting, nausea, and lethargy may also occur following overdosage.

Balmox Patient Information

Balmox Organisms Affected

Enteric bacteria and other eubacteria