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Arthaxan Brand names, Arthaxan Analogs

Arthaxan Brand Names Mixture

  • No information avaliable

Arthaxan Chemical_Formula


Arthaxan RX_link

Arthaxan fda sheet

Arthaxan FDA

Arthaxan msds (material safety sheet)

Arthaxan MSDS

Arthaxan Synthesis Reference

No information avaliable

Arthaxan Molecular Weight

232.235 g/mol

Arthaxan Melting Point

229.5 oC

Arthaxan H2O Solubility

100 mg/L

Arthaxan State


Arthaxan LogP


Arthaxan Dosage Forms

Suspension (250 mg/5 mL tsp); Tablets (1000 mg, 500 mg, 250 mg)

Arthaxan Indication

For the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of E. Coli, Enterobacter species, Klebsiella species, and Proteus species.

Arthaxan Pharmacology

Nalidixic acid is a quinolone antibacterial agent for oral administration. Nalidixic acid has marked antibacterial activity against gram-negative bacteria including Enterobacter species, Escherichia coli, Morganella Morganii; Proteus Mirabilis, Proteus vulgaris, and Providencia rettgeri. Pseudomonas species are generally resistant to the drug. Nalidixic acid is bactericidal and is effective over the entire urinary pH range. Conventional chromosomal resistance to nalidixic acid taken in full dosage has been reported to emerge in approximately 2 to 14 percent of patients during treatment; however, bacterial resistance to nalidixic acid has not been shown to be transferable via R factor.

Arthaxan Absorption

Following oral administration, nalidixic acid is rapidly absorbed from the gastrointestinal tract. Bioavailability is approximately 96%. Absorption may be delayed if taken with antacids.

Arthaxan side effects and Toxicity

ORAL (LD50): Acute: 1160 mg/kg [Rat]. 572 mg/kg [Mouse]. Toxic psychosis, convulsions, increased intracranial pressure, or metabolic acidosis may occur in patients taking more than the recommended dosage. Vomiting, nausea, and lethargy may also occur following overdosage.

Arthaxan Patient Information

Arthaxan Organisms Affected

Enteric bacteria and other eubacteria