Diethylcarbamazine
Brand names,
Diethylcarbamazine
Analogs
Diethylcarbamazine
Brand Names Mixture
- Drontal - Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Med. And Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Small Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tabs for Medium and Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
Diethylcarbamazine
Chemical_Formula
C10H21N3O
Diethylcarbamazine
RX_link
No information avaliable
Diethylcarbamazine
fda sheet
Diethylcarbamazine
msds (material safety sheet)
Diethylcarbamazine
Synthesis Reference
No information avaliable
Diethylcarbamazine
Molecular Weight
199.293 g/mol
Diethylcarbamazine
Melting Point
48 oC
Diethylcarbamazine
H2O Solubility
750 g/L at 20°C for the citrate salt.
Diethylcarbamazine
State
Solid
Diethylcarbamazine
LogP
-0.119
Diethylcarbamazine
Dosage Forms
Tablets (oral, 50mg)
Diethylcarbamazine
Indication
Used for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
Diethylcarbamazine
Pharmacology
Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. Diethylcarbamazine continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.
Diethylcarbamazine
Absorption
Readily absorbed following oral administration.
Diethylcarbamazine
side effects and Toxicity
Oral LD50 in rat and mouse is 1400 mg/kg and 660 mg/kg, respectively.
Diethylcarbamazine
Patient Information
Diethylcarbamazine
Organisms Affected
Humans, other mammals, parasitic nematodes and filarial worms