Ethodryl
Brand names,
Ethodryl
Analogs
Ethodryl
Brand Names Mixture
- Drontal - Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Med. And Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Small Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tabs for Medium and Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
Ethodryl
Chemical_Formula
C10H21N3O
Ethodryl
RX_link
No information avaliable
Ethodryl
fda sheet
Ethodryl
msds (material safety sheet)
Ethodryl
Synthesis Reference
No information avaliable
Ethodryl
Molecular Weight
199.293 g/mol
Ethodryl
Melting Point
48 oC
Ethodryl
H2O Solubility
750 g/L at 20°C for the citrate salt.
Ethodryl
State
Solid
Ethodryl
LogP
-0.119
Ethodryl
Dosage Forms
Tablets (oral, 50mg)
Ethodryl
Indication
Used for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
Ethodryl
Pharmacology
Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. Diethylcarbamazine continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.
Ethodryl
Absorption
Readily absorbed following oral administration.
Ethodryl
side effects and Toxicity
Oral LD50 in rat and mouse is 1400 mg/kg and 660 mg/kg, respectively.
Ethodryl
Patient Information
Ethodryl
Organisms Affected
Humans, other mammals, parasitic nematodes and filarial worms