Hetrazan
Brand names,
Hetrazan
Analogs
Hetrazan
Brand Names Mixture
- Drontal - Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Med. And Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Small Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tabs for Medium and Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
Hetrazan
Chemical_Formula
C10H21N3O
Hetrazan
RX_link
No information avaliable
Hetrazan
fda sheet
Hetrazan
msds (material safety sheet)
Hetrazan
Synthesis Reference
No information avaliable
Hetrazan
Molecular Weight
199.293 g/mol
Hetrazan
Melting Point
48 oC
Hetrazan
H2O Solubility
750 g/L at 20°C for the citrate salt.
Hetrazan
State
Solid
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LogP
-0.119
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Dosage Forms
Tablets (oral, 50mg)
Hetrazan
Indication
Used for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
Hetrazan
Pharmacology
Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. Diethylcarbamazine continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.
Hetrazan
Absorption
Readily absorbed following oral administration.
Hetrazan
side effects and Toxicity
Oral LD50 in rat and mouse is 1400 mg/kg and 660 mg/kg, respectively.
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Patient Information
Hetrazan
Organisms Affected
Humans, other mammals, parasitic nematodes and filarial worms