Notezine
Notezine Brand names, Notezine Analogs
Notezine Brand Names Mixture
- Drontal - Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Med. And Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Small Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tabs for Medium and Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
Notezine Chemical_Formula
C10H21N3O
Notezine RX_link
No information avaliable
Notezine fda sheet
Notezine msds (material safety sheet)
Notezine Synthesis Reference
No information avaliable
Notezine Molecular Weight
199.293 g/mol
Notezine Melting Point
48 oC
Notezine H2O Solubility
750 g/L at 20°C for the citrate salt.
Notezine State
Solid
Notezine LogP
-0.119
Notezine Dosage Forms
Tablets (oral, 50mg)
Notezine Indication
Used for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
Notezine Pharmacology
Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. Diethylcarbamazine continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.
Notezine Absorption
Readily absorbed following oral administration.
Notezine side effects and Toxicity
Oral LD50 in rat and mouse is 1400 mg/kg and 660 mg/kg, respectively.
Notezine Patient Information
Notezine Organisms Affected
Humans, other mammals, parasitic nematodes and filarial worms
