Ditrazine base
Ditrazine base Brand names, Ditrazine base Analogs
Ditrazine base Brand Names Mixture
- Drontal - Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Med. And Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Small Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tabs for Medium and Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
Ditrazine base Chemical_Formula
C10H21N3O
Ditrazine base RX_link
No information avaliable
Ditrazine base fda sheet
Ditrazine base msds (material safety sheet)
Ditrazine base Synthesis Reference
No information avaliable
Ditrazine base Molecular Weight
199.293 g/mol
Ditrazine base Melting Point
48 oC
Ditrazine base H2O Solubility
750 g/L at 20°C for the citrate salt.
Ditrazine base State
Solid
Ditrazine base LogP
-0.119
Ditrazine base Dosage Forms
Tablets (oral, 50mg)
Ditrazine base Indication
Used for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
Ditrazine base Pharmacology
Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. Diethylcarbamazine continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.
Ditrazine base Absorption
Readily absorbed following oral administration.
Ditrazine base side effects and Toxicity
Oral LD50 in rat and mouse is 1400 mg/kg and 660 mg/kg, respectively.
Ditrazine base Patient Information
Ditrazine base Organisms Affected
Humans, other mammals, parasitic nematodes and filarial worms
