Bitirazine
Bitirazine Brand names, Bitirazine Analogs
Bitirazine Brand Names Mixture
- Drontal - Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Med. And Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Small Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tabs for Medium and Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
Bitirazine Chemical_Formula
C10H21N3O
Bitirazine RX_link
No information avaliable
Bitirazine fda sheet
Bitirazine msds (material safety sheet)
Bitirazine Synthesis Reference
No information avaliable
Bitirazine Molecular Weight
199.293 g/mol
Bitirazine Melting Point
48 oC
Bitirazine H2O Solubility
750 g/L at 20°C for the citrate salt.
Bitirazine State
Solid
Bitirazine LogP
-0.119
Bitirazine Dosage Forms
Tablets (oral, 50mg)
Bitirazine Indication
Used for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
Bitirazine Pharmacology
Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. Diethylcarbamazine continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.
Bitirazine Absorption
Readily absorbed following oral administration.
Bitirazine side effects and Toxicity
Oral LD50 in rat and mouse is 1400 mg/kg and 660 mg/kg, respectively.
Bitirazine Patient Information
Bitirazine Organisms Affected
Humans, other mammals, parasitic nematodes and filarial worms
