Spatonin
Brand names,
Spatonin
Analogs
Spatonin
Brand Names Mixture
- Drontal - Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Med. And Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tablets for Small Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Plus Tabs for Medium and Large Dogs (Febantel + Praziquantel + Pyrantel (Pyrantel Pamoate))
- Drontal Tab (Praziquantel + Pyrantel (Pyrantel Pamoate))
Spatonin
Chemical_Formula
C10H21N3O
Spatonin
RX_link
No information avaliable
Spatonin
fda sheet
Spatonin
msds (material safety sheet)
Spatonin
Synthesis Reference
No information avaliable
Spatonin
Molecular Weight
199.293 g/mol
Spatonin
Melting Point
48 oC
Spatonin
H2O Solubility
750 g/L at 20°C for the citrate salt.
Spatonin
State
Solid
Spatonin
LogP
-0.119
Spatonin
Dosage Forms
Tablets (oral, 50mg)
Spatonin
Indication
Used for the treatment of individual patients with certain filarial diseases including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
Spatonin
Pharmacology
Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. Diethylcarbamazine continues to be the mainstay for treatment of patients with lymphatic filariasis and loiasis.
Spatonin
Absorption
Readily absorbed following oral administration.
Spatonin
side effects and Toxicity
Oral LD50 in rat and mouse is 1400 mg/kg and 660 mg/kg, respectively.
Spatonin
Patient Information
Spatonin
Organisms Affected
Humans, other mammals, parasitic nematodes and filarial worms