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Detrol Brand names, Detrol Analogs

Detrol Brand Names Mixture

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Detrol Chemical_Formula


Detrol RX_link

Detrol fda sheet

Detrol FDA

Detrol msds (material safety sheet)

Detrol Synthesis Reference

No information avaliable

Detrol Molecular Weight

325.488 g/mol

Detrol Melting Point

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Detrol H2O Solubility

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Detrol State


Detrol LogP


Detrol Dosage Forms

Capsule (sustained-release)

Detrol Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Detrol Pharmacology

Tolterodine is a competitive muscarinic receptor antagonist. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. After oral administration, tolterodine is metabolized in the liver, resulting in the formation of the 5-hydroxymethyl derivative, a major pharmacologically active metabolite. The 5-hydroxymethyl metabolite, which exhibits an antimuscarinic activity similar to that of tolterodine, contributes significantly to the therapeutic effect. Both tolterodine and the 5-hydroxymethyl metabolite exhibit a high specificity for muscarinic receptors, since both show negligible activity or affinity for other neurotransmitter receptors and other potential cellular targets, such as calcium channels. Tolterodine has a pronounced effect on bladder function. The main effects of tolterodine are an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, consistent with an antimuscarinic action on the lower urinary tract.

Detrol Absorption

No information avaliable

Detrol side effects and Toxicity

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Detrol Patient Information

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Detrol Organisms Affected

Humans and other mammals