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Detrol LA Brand names, Detrol LA Analogs

Detrol LA Brand Names Mixture

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Detrol LA Chemical_Formula


Detrol LA RX_link

Detrol LA fda sheet

Detrol_LA FDA

Detrol LA msds (material safety sheet)

Detrol LA Synthesis Reference

No information avaliable

Detrol LA Molecular Weight

325.488 g/mol

Detrol LA Melting Point

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Detrol LA H2O Solubility

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Detrol LA State


Detrol LA LogP


Detrol LA Dosage Forms

Capsule (sustained-release)

Detrol LA Indication

For the treatment of overactive bladder (with symptoms of urinary frequency, urgency, or urge incontinence).

Detrol LA Pharmacology

Tolterodine is a competitive muscarinic receptor antagonist. Both urinary bladder contraction and salivation are mediated via cholinergic muscarinic receptors. After oral administration, tolterodine is metabolized in the liver, resulting in the formation of the 5-hydroxymethyl derivative, a major pharmacologically active metabolite. The 5-hydroxymethyl metabolite, which exhibits an antimuscarinic activity similar to that of tolterodine, contributes significantly to the therapeutic effect. Both tolterodine and the 5-hydroxymethyl metabolite exhibit a high specificity for muscarinic receptors, since both show negligible activity or affinity for other neurotransmitter receptors and other potential cellular targets, such as calcium channels. Tolterodine has a pronounced effect on bladder function. The main effects of tolterodine are an increase in residual urine, reflecting an incomplete emptying of the bladder, and a decrease in detrusor pressure, consistent with an antimuscarinic action on the lower urinary tract.

Detrol LA Absorption

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Detrol LA side effects and Toxicity

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Detrol LA Patient Information

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Detrol LA Organisms Affected

Humans and other mammals