Cyclopentolate HCL
Brand names,
Cyclopentolate HCL
Analogs
Cyclopentolate HCL
Brand Names Mixture
Cyclopentolate HCL
Chemical_Formula
C17H25NO3
Cyclopentolate HCL
RX_link
No information avaliable
Cyclopentolate HCL
fda sheet
Cyclopentolate HCL
msds (material safety sheet)
Cyclopentolate HCL
Synthesis Reference
No information avaliable
Cyclopentolate HCL
Molecular Weight
291.385 g/mol
Cyclopentolate HCL
Melting Point
139 oC (hydrochloride salt)
Cyclopentolate HCL
H2O Solubility
No information avaliable
Cyclopentolate HCL
State
Solid
Cyclopentolate HCL
LogP
3.124
Cyclopentolate HCL
Dosage Forms
Ophthalmic solution (eye drops)
Cyclopentolate HCL
Indication
Used mainly to produce mydriasis and cycloplegia for diagnostic purposes.
Cyclopentolate HCL
Pharmacology
Cyclopentolate is an anti-muscarinic in the same class as atropine and scopolamine. Cyclopentolate blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. Cyclopentolate thus induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours. The cycloplegic and mydriatic effects are slower in onset and longer in duration in patients who have dark pigmented irises.
Cyclopentolate HCL
Absorption
Absorbed following ophthalmic administration.
Cyclopentolate HCL
side effects and Toxicity
Oral LD50 in the rat is 4000 mg/kg and 960 mg/kg in the mouse. Symptoms of overdose include tachycardia, dizziness, dry mouth, behavioral disturbances, uncoordination and drowsiness.
Cyclopentolate HCL
Patient Information
No information avaliable
Cyclopentolate HCL
Organisms Affected
Humans and other mammals