yclopentolate
Brand names,
yclopentolate
Analogs
yclopentolate
Brand Names Mixture
yclopentolate
Chemical_Formula
C17H25NO3
yclopentolate
RX_link
No information avaliable
yclopentolate
fda sheet
yclopentolate
msds (material safety sheet)
yclopentolate
Synthesis Reference
No information avaliable
yclopentolate
Molecular Weight
291.385 g/mol
yclopentolate
Melting Point
139 oC (hydrochloride salt)
yclopentolate
H2O Solubility
No information avaliable
yclopentolate
State
Solid
yclopentolate
LogP
3.124
yclopentolate
Dosage Forms
Ophthalmic solution (eye drops)
yclopentolate
Indication
Used mainly to produce mydriasis and cycloplegia for diagnostic purposes.
yclopentolate
Pharmacology
Cyclopentolate is an anti-muscarinic in the same class as atropine and scopolamine. Cyclopentolate blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. Cyclopentolate thus induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours. The cycloplegic and mydriatic effects are slower in onset and longer in duration in patients who have dark pigmented irises.
yclopentolate
Absorption
Absorbed following ophthalmic administration.
yclopentolate
side effects and Toxicity
Oral LD50 in the rat is 4000 mg/kg and 960 mg/kg in the mouse. Symptoms of overdose include tachycardia, dizziness, dry mouth, behavioral disturbances, uncoordination and drowsiness.
yclopentolate
Patient Information
No information avaliable
yclopentolate
Organisms Affected
Humans and other mammals