Mydrilate
Mydrilate Brand names, Mydrilate Analogs
Mydrilate Brand Names Mixture
- No information avaliable
Mydrilate Chemical_Formula
C17H25NO3
Mydrilate RX_link
No information avaliable
Mydrilate fda sheet
Mydrilate msds (material safety sheet)
Mydrilate Synthesis Reference
No information avaliable
Mydrilate Molecular Weight
291.385 g/mol
Mydrilate Melting Point
139 oC (hydrochloride salt)
Mydrilate H2O Solubility
No information avaliable
Mydrilate State
Solid
Mydrilate LogP
3.124
Mydrilate Dosage Forms
Ophthalmic solution (eye drops)
Mydrilate Indication
Used mainly to produce mydriasis and cycloplegia for diagnostic purposes.
Mydrilate Pharmacology
Cyclopentolate is an anti-muscarinic in the same class as atropine and scopolamine. Cyclopentolate blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. Cyclopentolate thus induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours. The cycloplegic and mydriatic effects are slower in onset and longer in duration in patients who have dark pigmented irises.
Mydrilate Absorption
Absorbed following ophthalmic administration.
Mydrilate side effects and Toxicity
Oral LD50 in the rat is 4000 mg/kg and 960 mg/kg in the mouse. Symptoms of overdose include tachycardia, dizziness, dry mouth, behavioral disturbances, uncoordination and drowsiness.
Mydrilate Patient Information
No information avaliable
Mydrilate Organisms Affected
Humans and other mammals
