Diopentolate
Diopentolate Brand names, Diopentolate Analogs
Diopentolate Brand Names Mixture
- No information avaliable
Diopentolate Chemical_Formula
C17H25NO3
Diopentolate RX_link
No information avaliable
Diopentolate fda sheet
Diopentolate msds (material safety sheet)
Diopentolate Synthesis Reference
No information avaliable
Diopentolate Molecular Weight
291.385 g/mol
Diopentolate Melting Point
139 oC (hydrochloride salt)
Diopentolate H2O Solubility
No information avaliable
Diopentolate State
Solid
Diopentolate LogP
3.124
Diopentolate Dosage Forms
Ophthalmic solution (eye drops)
Diopentolate Indication
Used mainly to produce mydriasis and cycloplegia for diagnostic purposes.
Diopentolate Pharmacology
Cyclopentolate is an anti-muscarinic in the same class as atropine and scopolamine. Cyclopentolate blocks the receptors in the muscles of the eye (muscarinic receptors). These receptors are involved controlling the pupil size and the shape of the lens. Cyclopentolate thus induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours. The cycloplegic and mydriatic effects are slower in onset and longer in duration in patients who have dark pigmented irises.
Diopentolate Absorption
Absorbed following ophthalmic administration.
Diopentolate side effects and Toxicity
Oral LD50 in the rat is 4000 mg/kg and 960 mg/kg in the mouse. Symptoms of overdose include tachycardia, dizziness, dry mouth, behavioral disturbances, uncoordination and drowsiness.
Diopentolate Patient Information
No information avaliable
Diopentolate Organisms Affected
Humans and other mammals
