Chlorprothixene
Brand names,
Chlorprothixene
Analogs
Chlorprothixene
Brand Names Mixture
Chlorprothixene
Chemical_Formula
C18H18ClNS
Chlorprothixene
RX_link
No information avaliable
Chlorprothixene
fda sheet
Chlorprothixene
msds (material safety sheet)
Chlorprothixene
Synthesis Reference
No information avaliable
Chlorprothixene
Molecular Weight
315.861 g/mol
Chlorprothixene
Melting Point
97.5 oC
Chlorprothixene
H2O Solubility
0.295 mg/L
Chlorprothixene
State
Solid
Chlorprothixene
LogP
5.654
Chlorprothixene
Dosage Forms
Tablets; Syrup (concentrate)
Chlorprothixene
Indication
For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
Chlorprothixene
Pharmacology
Chlorprothixene is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). An intrinsic antidepressant effect of chlorprothixene has been discussed, but not proven yet. Likewise, it is unclear, if chlorprothixene has genuine analgesic effects. An antiemetic effect, as with most antipsychotics, exists. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixene has a strong sedative activity with a high incidence of anticholinergic side-effects. Chlorprothixene is structurally related to chlorpromazine, with which it shares in principal all side effects. Allergic side-effects and liver damage seem to appear with an appreciable lower frequency.
Chlorprothixene
Absorption
No information avaliable
Chlorprothixene
side effects and Toxicity
Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).
Chlorprothixene
Patient Information
Chlorprothixene
Organisms Affected
Humans and other mammals