Chlothixen
Brand names,
Chlothixen
Analogs
Chlothixen
Brand Names Mixture
Chlothixen
Chemical_Formula
C18H18ClNS
Chlothixen
RX_link
No information avaliable
Chlothixen
fda sheet
Chlothixen
msds (material safety sheet)
Chlothixen
Synthesis Reference
No information avaliable
Chlothixen
Molecular Weight
315.861 g/mol
Chlothixen
Melting Point
97.5 oC
Chlothixen
H2O Solubility
0.295 mg/L
Chlothixen
State
Solid
Chlothixen
LogP
5.654
Chlothixen
Dosage Forms
Tablets; Syrup (concentrate)
Chlothixen
Indication
For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
Chlothixen
Pharmacology
Chlorprothixene is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). An intrinsic antidepressant effect of chlorprothixene has been discussed, but not proven yet. Likewise, it is unclear, if chlorprothixene has genuine analgesic effects. An antiemetic effect, as with most antipsychotics, exists. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixene has a strong sedative activity with a high incidence of anticholinergic side-effects. Chlorprothixene is structurally related to chlorpromazine, with which it shares in principal all side effects. Allergic side-effects and liver damage seem to appear with an appreciable lower frequency.
Chlothixen
Absorption
No information avaliable
Chlothixen
side effects and Toxicity
Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).
Chlothixen
Patient Information
Chlothixen
Organisms Affected
Humans and other mammals