Chlorprotixine
Brand names,
Chlorprotixine
Analogs
Chlorprotixine
Brand Names Mixture
Chlorprotixine
Chemical_Formula
C18H18ClNS
Chlorprotixine
RX_link
No information avaliable
Chlorprotixine
fda sheet
Chlorprotixine
msds (material safety sheet)
Chlorprotixine
Synthesis Reference
No information avaliable
Chlorprotixine
Molecular Weight
315.861 g/mol
Chlorprotixine
Melting Point
97.5 oC
Chlorprotixine
H2O Solubility
0.295 mg/L
Chlorprotixine
State
Solid
Chlorprotixine
LogP
5.654
Chlorprotixine
Dosage Forms
Tablets; Syrup (concentrate)
Chlorprotixine
Indication
For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
Chlorprotixine
Pharmacology
Chlorprothixene is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). An intrinsic antidepressant effect of chlorprothixene has been discussed, but not proven yet. Likewise, it is unclear, if chlorprothixene has genuine analgesic effects. An antiemetic effect, as with most antipsychotics, exists. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixene has a strong sedative activity with a high incidence of anticholinergic side-effects. Chlorprothixene is structurally related to chlorpromazine, with which it shares in principal all side effects. Allergic side-effects and liver damage seem to appear with an appreciable lower frequency.
Chlorprotixine
Absorption
No information avaliable
Chlorprotixine
side effects and Toxicity
Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).
Chlorprotixine
Patient Information
Chlorprotixine
Organisms Affected
Humans and other mammals