Chlorprothixine
Brand names,
Chlorprothixine
Analogs
Chlorprothixine
Brand Names Mixture
Chlorprothixine
Chemical_Formula
C18H18ClNS
Chlorprothixine
RX_link
No information avaliable
Chlorprothixine
fda sheet
Chlorprothixine
msds (material safety sheet)
Chlorprothixine
Synthesis Reference
No information avaliable
Chlorprothixine
Molecular Weight
315.861 g/mol
Chlorprothixine
Melting Point
97.5 oC
Chlorprothixine
H2O Solubility
0.295 mg/L
Chlorprothixine
State
Solid
Chlorprothixine
LogP
5.654
Chlorprothixine
Dosage Forms
Tablets; Syrup (concentrate)
Chlorprothixine
Indication
For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
Chlorprothixine
Pharmacology
Chlorprothixene is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). An intrinsic antidepressant effect of chlorprothixene has been discussed, but not proven yet. Likewise, it is unclear, if chlorprothixene has genuine analgesic effects. An antiemetic effect, as with most antipsychotics, exists. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixene has a strong sedative activity with a high incidence of anticholinergic side-effects. Chlorprothixene is structurally related to chlorpromazine, with which it shares in principal all side effects. Allergic side-effects and liver damage seem to appear with an appreciable lower frequency.
Chlorprothixine
Absorption
No information avaliable
Chlorprothixine
side effects and Toxicity
Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).
Chlorprothixine
Patient Information
Chlorprothixine
Organisms Affected
Humans and other mammals