Chlorprotixene
Brand names,
Chlorprotixene
Analogs
Chlorprotixene
Brand Names Mixture
Chlorprotixene
Chemical_Formula
C18H18ClNS
Chlorprotixene
RX_link
No information avaliable
Chlorprotixene
fda sheet
Chlorprotixene
msds (material safety sheet)
Chlorprotixene
Synthesis Reference
No information avaliable
Chlorprotixene
Molecular Weight
315.861 g/mol
Chlorprotixene
Melting Point
97.5 oC
Chlorprotixene
H2O Solubility
0.295 mg/L
Chlorprotixene
State
Solid
Chlorprotixene
LogP
5.654
Chlorprotixene
Dosage Forms
Tablets; Syrup (concentrate)
Chlorprotixene
Indication
For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
Chlorprotixene
Pharmacology
Chlorprothixene is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). An intrinsic antidepressant effect of chlorprothixene has been discussed, but not proven yet. Likewise, it is unclear, if chlorprothixene has genuine analgesic effects. An antiemetic effect, as with most antipsychotics, exists. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixene has a strong sedative activity with a high incidence of anticholinergic side-effects. Chlorprothixene is structurally related to chlorpromazine, with which it shares in principal all side effects. Allergic side-effects and liver damage seem to appear with an appreciable lower frequency.
Chlorprotixene
Absorption
No information avaliable
Chlorprotixene
side effects and Toxicity
Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).
Chlorprotixene
Patient Information
Chlorprotixene
Organisms Affected
Humans and other mammals