Chloroprothixene
Brand names,
Chloroprothixene
Analogs
Chloroprothixene
Brand Names Mixture
Chloroprothixene
Chemical_Formula
C18H18ClNS
Chloroprothixene
RX_link
No information avaliable
Chloroprothixene
fda sheet
Chloroprothixene
msds (material safety sheet)
Chloroprothixene
Synthesis Reference
No information avaliable
Chloroprothixene
Molecular Weight
315.861 g/mol
Chloroprothixene
Melting Point
97.5 oC
Chloroprothixene
H2O Solubility
0.295 mg/L
Chloroprothixene
State
Solid
Chloroprothixene
LogP
5.654
Chloroprothixene
Dosage Forms
Tablets; Syrup (concentrate)
Chloroprothixene
Indication
For treatment of psychotic disorders (e.g. schizophrenia) and of acute mania occuring as part of bipolar disorders.
Chloroprothixene
Pharmacology
Chlorprothixene is a typical antipsychotic drug of the thioxanthine class. It has a low antipsychotic potency (half to 2/3 of chlorpromazine). An intrinsic antidepressant effect of chlorprothixene has been discussed, but not proven yet. Likewise, it is unclear, if chlorprothixene has genuine analgesic effects. An antiemetic effect, as with most antipsychotics, exists. It is used in the treatment of nervous, mental, and emotional conditions. Improvement in such conditions is thought to result from the effect of the medicine on nerve pathways in specific areas of the brain. Chlorprothixene has a strong sedative activity with a high incidence of anticholinergic side-effects. Chlorprothixene is structurally related to chlorpromazine, with which it shares in principal all side effects. Allergic side-effects and liver damage seem to appear with an appreciable lower frequency.
Chloroprothixene
Absorption
No information avaliable
Chloroprothixene
side effects and Toxicity
Symptoms of overdose include difficulty in breathing (severe), dizziness (severe), drowsiness (severe), muscle trembling, jerking, stiffness, or uncontrolled movements (severe), small pupils, unusual excitement, and unusual tiredness or weakness (severe).
Chloroprothixene
Patient Information
Chloroprothixene
Organisms Affected
Humans and other mammals