Anileridine
Brand names,
Anileridine
Analogs
Anileridine
Brand Names Mixture
Anileridine
Chemical_Formula
C22H28N2O2
Anileridine
RX_link
No information avaliable
Anileridine
fda sheet
Anileridine
msds (material safety sheet)
Anileridine
Synthesis Reference
Weijlard et al., J. Am. Chem. Soc. 78, 2342 (1956)
Anileridine
Molecular Weight
352.47 g/mol
Anileridine
Melting Point
83 oC
Anileridine
H2O Solubility
No information avaliable
Anileridine
State
Solid
Anileridine
LogP
4.384
Anileridine
Dosage Forms
Liquid; Tablet
Anileridine
Indication
For treatment and management of pain (systemic) and for use as an anesthesia adjunct.
Anileridine
Pharmacology
Anileridine, a potent analgesic, is an analog of pethidine. Anileridine is useful for the relief of moderate to severe pain. It may also be used as an analgesic adjunct in general anesthesia in the same manner as meperidine to reduce the amount of anesthetic needed, to facilitate relaxation, and to reduce laryngospasm. In addition, anileridine exerts mild antihistaminic, spasmolytic and antitussive effects. Anileridine's main pharmacologic action is exerted on the CNS. Respiratory depression, when it occurs, is of shorter duration than that seen with morphine or meperidine when equipotent analgesic doses are used.
Anileridine
Absorption
Anileridine is absorbed by all routes of administration.
Anileridine
side effects and Toxicity
Symptoms of overexposure include dizziness, perspiration, a feeling of warmth, dry mouth, visual difficulty, itching, euphoria, restlessness, nervousness and excitement have been reported.
Anileridine
Patient Information
No information avaliable
Anileridine
Organisms Affected
Humans and other mammals