Nipecotan
Brand names,
Nipecotan
Analogs
Nipecotan
Brand Names Mixture
Nipecotan
Chemical_Formula
C22H28N2O2
Nipecotan
RX_link
No information avaliable
Nipecotan
fda sheet
Nipecotan
msds (material safety sheet)
Nipecotan
Synthesis Reference
Weijlard et al., J. Am. Chem. Soc. 78, 2342 (1956)
Nipecotan
Molecular Weight
352.47 g/mol
Nipecotan
Melting Point
83 oC
Nipecotan
H2O Solubility
No information avaliable
Nipecotan
State
Solid
Nipecotan
LogP
4.384
Nipecotan
Dosage Forms
Liquid; Tablet
Nipecotan
Indication
For treatment and management of pain (systemic) and for use as an anesthesia adjunct.
Nipecotan
Pharmacology
Anileridine, a potent analgesic, is an analog of pethidine. Anileridine is useful for the relief of moderate to severe pain. It may also be used as an analgesic adjunct in general anesthesia in the same manner as meperidine to reduce the amount of anesthetic needed, to facilitate relaxation, and to reduce laryngospasm. In addition, anileridine exerts mild antihistaminic, spasmolytic and antitussive effects. Anileridine's main pharmacologic action is exerted on the CNS. Respiratory depression, when it occurs, is of shorter duration than that seen with morphine or meperidine when equipotent analgesic doses are used.
Nipecotan
Absorption
Anileridine is absorbed by all routes of administration.
Nipecotan
side effects and Toxicity
Symptoms of overexposure include dizziness, perspiration, a feeling of warmth, dry mouth, visual difficulty, itching, euphoria, restlessness, nervousness and excitement have been reported.
Nipecotan
Patient Information
No information avaliable
Nipecotan
Organisms Affected
Humans and other mammals