Adopol
Brand names,
Adopol
Analogs
Adopol
Brand Names Mixture
Adopol
Chemical_Formula
C22H28N2O2
Adopol
RX_link
No information avaliable
Adopol
fda sheet
Adopol
msds (material safety sheet)
Adopol
Synthesis Reference
Weijlard et al., J. Am. Chem. Soc. 78, 2342 (1956)
Adopol
Molecular Weight
352.47 g/mol
Adopol
Melting Point
83 oC
Adopol
H2O Solubility
No information avaliable
Adopol
State
Solid
Adopol
LogP
4.384
Adopol
Dosage Forms
Liquid; Tablet
Adopol
Indication
For treatment and management of pain (systemic) and for use as an anesthesia adjunct.
Adopol
Pharmacology
Anileridine, a potent analgesic, is an analog of pethidine. Anileridine is useful for the relief of moderate to severe pain. It may also be used as an analgesic adjunct in general anesthesia in the same manner as meperidine to reduce the amount of anesthetic needed, to facilitate relaxation, and to reduce laryngospasm. In addition, anileridine exerts mild antihistaminic, spasmolytic and antitussive effects. Anileridine's main pharmacologic action is exerted on the CNS. Respiratory depression, when it occurs, is of shorter duration than that seen with morphine or meperidine when equipotent analgesic doses are used.
Adopol
Absorption
Anileridine is absorbed by all routes of administration.
Adopol
side effects and Toxicity
Symptoms of overexposure include dizziness, perspiration, a feeling of warmth, dry mouth, visual difficulty, itching, euphoria, restlessness, nervousness and excitement have been reported.
Adopol
Patient Information
No information avaliable
Adopol
Organisms Affected
Humans and other mammals