Apidol
Brand names,
Apidol
Analogs
Apidol
Brand Names Mixture
Apidol
Chemical_Formula
C22H28N2O2
Apidol
RX_link
No information avaliable
Apidol
fda sheet
Apidol
msds (material safety sheet)
Apidol
Synthesis Reference
Weijlard et al., J. Am. Chem. Soc. 78, 2342 (1956)
Apidol
Molecular Weight
352.47 g/mol
Apidol
Melting Point
83 oC
Apidol
H2O Solubility
No information avaliable
Apidol
State
Solid
Apidol
LogP
4.384
Apidol
Dosage Forms
Liquid; Tablet
Apidol
Indication
For treatment and management of pain (systemic) and for use as an anesthesia adjunct.
Apidol
Pharmacology
Anileridine, a potent analgesic, is an analog of pethidine. Anileridine is useful for the relief of moderate to severe pain. It may also be used as an analgesic adjunct in general anesthesia in the same manner as meperidine to reduce the amount of anesthetic needed, to facilitate relaxation, and to reduce laryngospasm. In addition, anileridine exerts mild antihistaminic, spasmolytic and antitussive effects. Anileridine's main pharmacologic action is exerted on the CNS. Respiratory depression, when it occurs, is of shorter duration than that seen with morphine or meperidine when equipotent analgesic doses are used.
Apidol
Absorption
Anileridine is absorbed by all routes of administration.
Apidol
side effects and Toxicity
Symptoms of overexposure include dizziness, perspiration, a feeling of warmth, dry mouth, visual difficulty, itching, euphoria, restlessness, nervousness and excitement have been reported.
Apidol
Patient Information
No information avaliable
Apidol
Organisms Affected
Humans and other mammals