Leritine
Brand names,
Leritine
Analogs
Leritine
Brand Names Mixture
Leritine
Chemical_Formula
C22H28N2O2
Leritine
RX_link
No information avaliable
Leritine
fda sheet
Leritine
msds (material safety sheet)
Leritine
Synthesis Reference
Weijlard et al., J. Am. Chem. Soc. 78, 2342 (1956)
Leritine
Molecular Weight
352.47 g/mol
Leritine
Melting Point
83 oC
Leritine
H2O Solubility
No information avaliable
Leritine
State
Solid
Leritine
LogP
4.384
Leritine
Dosage Forms
Liquid; Tablet
Leritine
Indication
For treatment and management of pain (systemic) and for use as an anesthesia adjunct.
Leritine
Pharmacology
Anileridine, a potent analgesic, is an analog of pethidine. Anileridine is useful for the relief of moderate to severe pain. It may also be used as an analgesic adjunct in general anesthesia in the same manner as meperidine to reduce the amount of anesthetic needed, to facilitate relaxation, and to reduce laryngospasm. In addition, anileridine exerts mild antihistaminic, spasmolytic and antitussive effects. Anileridine's main pharmacologic action is exerted on the CNS. Respiratory depression, when it occurs, is of shorter duration than that seen with morphine or meperidine when equipotent analgesic doses are used.
Leritine
Absorption
Anileridine is absorbed by all routes of administration.
Leritine
side effects and Toxicity
Symptoms of overexposure include dizziness, perspiration, a feeling of warmth, dry mouth, visual difficulty, itching, euphoria, restlessness, nervousness and excitement have been reported.
Leritine
Patient Information
No information avaliable
Leritine
Organisms Affected
Humans and other mammals