Alidine
Brand names,
Alidine
Analogs
Alidine
Brand Names Mixture
Alidine
Chemical_Formula
C22H28N2O2
Alidine
RX_link
No information avaliable
Alidine
fda sheet
Alidine
msds (material safety sheet)
Alidine
Synthesis Reference
Weijlard et al., J. Am. Chem. Soc. 78, 2342 (1956)
Alidine
Molecular Weight
352.47 g/mol
Alidine
Melting Point
83 oC
Alidine
H2O Solubility
No information avaliable
Alidine
State
Solid
Alidine
LogP
4.384
Alidine
Dosage Forms
Liquid; Tablet
Alidine
Indication
For treatment and management of pain (systemic) and for use as an anesthesia adjunct.
Alidine
Pharmacology
Anileridine, a potent analgesic, is an analog of pethidine. Anileridine is useful for the relief of moderate to severe pain. It may also be used as an analgesic adjunct in general anesthesia in the same manner as meperidine to reduce the amount of anesthetic needed, to facilitate relaxation, and to reduce laryngospasm. In addition, anileridine exerts mild antihistaminic, spasmolytic and antitussive effects. Anileridine's main pharmacologic action is exerted on the CNS. Respiratory depression, when it occurs, is of shorter duration than that seen with morphine or meperidine when equipotent analgesic doses are used.
Alidine
Absorption
Anileridine is absorbed by all routes of administration.
Alidine
side effects and Toxicity
Symptoms of overexposure include dizziness, perspiration, a feeling of warmth, dry mouth, visual difficulty, itching, euphoria, restlessness, nervousness and excitement have been reported.
Alidine
Patient Information
No information avaliable
Alidine
Organisms Affected
Humans and other mammals