Apodol
Brand names,
Apodol
Analogs
Apodol
Brand Names Mixture
Apodol
Chemical_Formula
C22H28N2O2
Apodol
RX_link
No information avaliable
Apodol
fda sheet
Apodol
msds (material safety sheet)
Apodol
Synthesis Reference
Weijlard et al., J. Am. Chem. Soc. 78, 2342 (1956)
Apodol
Molecular Weight
352.47 g/mol
Apodol
Melting Point
83 oC
Apodol
H2O Solubility
No information avaliable
Apodol
State
Solid
Apodol
LogP
4.384
Apodol
Dosage Forms
Liquid; Tablet
Apodol
Indication
For treatment and management of pain (systemic) and for use as an anesthesia adjunct.
Apodol
Pharmacology
Anileridine, a potent analgesic, is an analog of pethidine. Anileridine is useful for the relief of moderate to severe pain. It may also be used as an analgesic adjunct in general anesthesia in the same manner as meperidine to reduce the amount of anesthetic needed, to facilitate relaxation, and to reduce laryngospasm. In addition, anileridine exerts mild antihistaminic, spasmolytic and antitussive effects. Anileridine's main pharmacologic action is exerted on the CNS. Respiratory depression, when it occurs, is of shorter duration than that seen with morphine or meperidine when equipotent analgesic doses are used.
Apodol
Absorption
Anileridine is absorbed by all routes of administration.
Apodol
side effects and Toxicity
Symptoms of overexposure include dizziness, perspiration, a feeling of warmth, dry mouth, visual difficulty, itching, euphoria, restlessness, nervousness and excitement have been reported.
Apodol
Patient Information
No information avaliable
Apodol
Organisms Affected
Humans and other mammals