Amsidyl
Brand names,
Amsidyl
Analogs
Amsidyl
Brand Names Mixture
Amsidyl
Chemical_Formula
C21H19N3O3S
Amsidyl
RX_link
No information avaliable
Amsidyl
fda sheet
Amsidyl
msds (material safety sheet)
Amsidyl
Synthesis Reference
No information avaliable
Amsidyl
Molecular Weight
393.46 g/mol
Amsidyl
Melting Point
234-236oC
Amsidyl
H2O Solubility
<1 mg/mL
Amsidyl
State
Solid
Amsidyl
LogP
5.273
Amsidyl
Dosage Forms
Liquid
Amsidyl
Indication
For treatment of acute myeloid leukaemia.
Amsidyl
Pharmacology
Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Amsidyl
Absorption
Poorly absorbed
Amsidyl
side effects and Toxicity
Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).
Amsidyl
Patient Information
No information avaliable
Amsidyl
Organisms Affected
Humans and other mammals