Amsidine
Amsidine Brand names, Amsidine Analogs
Amsidine Brand Names Mixture
- No information avaliable
Amsidine Chemical_Formula
C21H19N3O3S
Amsidine RX_link
No information avaliable
Amsidine fda sheet
Amsidine msds (material safety sheet)
Amsidine Synthesis Reference
No information avaliable
Amsidine Molecular Weight
393.46 g/mol
Amsidine Melting Point
234-236oC
Amsidine H2O Solubility
<1 mg/mL
Amsidine State
Solid
Amsidine LogP
5.273
Amsidine Dosage Forms
Liquid
Amsidine Indication
For treatment of acute myeloid leukaemia.
Amsidine Pharmacology
Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Amsidine Absorption
Poorly absorbed
Amsidine side effects and Toxicity
Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).
Amsidine Patient Information
No information avaliable
Amsidine Organisms Affected
Humans and other mammals
