MAMSA
MAMSA Brand names, MAMSA Analogs
MAMSA Brand Names Mixture
- No information avaliable
MAMSA Chemical_Formula
C21H19N3O3S
MAMSA RX_link
No information avaliable
MAMSA fda sheet
MAMSA msds (material safety sheet)
MAMSA Synthesis Reference
No information avaliable
MAMSA Molecular Weight
393.46 g/mol
MAMSA Melting Point
234-236oC
MAMSA H2O Solubility
<1 mg/mL
MAMSA State
Solid
MAMSA LogP
5.273
MAMSA Dosage Forms
Liquid
MAMSA Indication
For treatment of acute myeloid leukaemia.
MAMSA Pharmacology
Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
MAMSA Absorption
Poorly absorbed
MAMSA side effects and Toxicity
Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).
MAMSA Patient Information
No information avaliable
MAMSA Organisms Affected
Humans and other mammals
