AMSA P-D
AMSA P-D Brand names, AMSA P-D Analogs
AMSA P-D Brand Names Mixture
- No information avaliable
AMSA P-D Chemical_Formula
C21H19N3O3S
AMSA P-D RX_link
No information avaliable
AMSA P-D fda sheet
AMSA P-D msds (material safety sheet)
AMSA P-D Synthesis Reference
No information avaliable
AMSA P-D Molecular Weight
393.46 g/mol
AMSA P-D Melting Point
234-236oC
AMSA P-D H2O Solubility
<1 mg/mL
AMSA P-D State
Solid
AMSA P-D LogP
5.273
AMSA P-D Dosage Forms
Liquid
AMSA P-D Indication
For treatment of acute myeloid leukaemia.
AMSA P-D Pharmacology
Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
AMSA P-D Absorption
Poorly absorbed
AMSA P-D side effects and Toxicity
Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).
AMSA P-D Patient Information
No information avaliable
AMSA P-D Organisms Affected
Humans and other mammals
