Amsine
Amsine Brand names, Amsine Analogs
Amsine Brand Names Mixture
- No information avaliable
Amsine Chemical_Formula
C21H19N3O3S
Amsine RX_link
No information avaliable
Amsine fda sheet
Amsine msds (material safety sheet)
Amsine Synthesis Reference
No information avaliable
Amsine Molecular Weight
393.46 g/mol
Amsine Melting Point
234-236oC
Amsine H2O Solubility
<1 mg/mL
Amsine State
Solid
Amsine LogP
5.273
Amsine Dosage Forms
Liquid
Amsine Indication
For treatment of acute myeloid leukaemia.
Amsine Pharmacology
Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Amsine Absorption
Poorly absorbed
Amsine side effects and Toxicity
Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).
Amsine Patient Information
No information avaliable
Amsine Organisms Affected
Humans and other mammals
