Acridinyl Anisidide
Brand names,
Acridinyl Anisidide
Analogs
Acridinyl Anisidide
Brand Names Mixture
Acridinyl Anisidide
Chemical_Formula
C21H19N3O3S
Acridinyl Anisidide
RX_link
No information avaliable
Acridinyl Anisidide
fda sheet
Acridinyl Anisidide
msds (material safety sheet)
Acridinyl Anisidide
Synthesis Reference
No information avaliable
Acridinyl Anisidide
Molecular Weight
393.46 g/mol
Acridinyl Anisidide
Melting Point
234-236oC
Acridinyl Anisidide
H2O Solubility
<1 mg/mL
Acridinyl Anisidide
State
Solid
Acridinyl Anisidide
LogP
5.273
Acridinyl Anisidide
Dosage Forms
Liquid
Acridinyl Anisidide
Indication
For treatment of acute myeloid leukaemia.
Acridinyl Anisidide
Pharmacology
Amsacrine is an aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Acridinyl Anisidide
Absorption
Poorly absorbed
Acridinyl Anisidide
side effects and Toxicity
Symptoms of overdose include nausea and vomiting, diarrhea, some cardiotoxicity (rarely).
Acridinyl Anisidide
Patient Information
No information avaliable
Acridinyl Anisidide
Organisms Affected
Humans and other mammals